Analysis of Large-Amplitude Pulses in Short Time Intervals: Application to Neuron Interactions
نویسندگان
چکیده
This paper deals with the analysis of a nonlinear dynamical system which characterizes the axons interaction and is based on a generalization of FitzHugh-Nagumo system. The parametric domain of stability is investigated for both the linear and third-order approximation. A further generalization is studied in presence of high-amplitude time-dependent pulse. The corresponding numerical solution for some given values of parameters are analyzed through the wavelet coefficients, showing both the sensitivity to local jumps and some unexpected inertia of neuron’s as response to the high-amplitude spike.
منابع مشابه
Comparison of the effect of quasitrapezoidal and rectangular pulses on bio- electrical activity, calcium spike properties and afterhyperpolarization potentials of Fl cells of Helix aspersa using intracellular recording
While the effect of changes of stimulus waveform (quasitrapezoidal and rectangular current pulses) on nerve activation is clear, but there is no evidence on the effect of quasitrapezoidal pulses on ionic currents of cellular membrane. In the present study, the effect of depolarizing quasi-trapezoidal current pulses, in comparison with that of depolarizing rectangular current pulses, on firing...
متن کاملMemristor Bridge Synapse Application for Integrate and Fire and Hodgkin-Huxley Neuron Cell
Memory resistor or memristor is already fabricated successfully using current nano dimension technology. Based on its unique hysteresis, the amount of resistance remains constant over time, controlled by the time, the amplitude, and the polarity of the applied voltage. The unique hysteretic current-voltage characteristic in the memristor causes this element to act as a non-volatile resistive me...
متن کاملEffects of Geometric Nonlinearity on Stress Analysis in Large Amplitude Vibration of Moderately Thick Annular Functionally Graded Plate
This paper deals with the nonlinear free vibration of thick annular functionally graded material plates. The thickness is assumed to be constant. Material properties are assumed to be graded in the thickness direction according to a simple power law distribution in terms of the volume fractions of the constituents. The formulations are based on the first-order shear deformation plate theory and...
متن کاملEffects of resveratrol on intrinsic neuronal properties of CA1 pyramidal neurons in rat hippocampal slices
Introduction: Resveratrol (3,5,4-trihydroxystilbene) a non-flavonoid polyphenol found in some plants like grapes, peanuts and pomegranates, possesses a wide range of biological effects. Evidence indicates that resveratrol has beneficial effects on nervous system to induce neuroprotection. However, the cellular mechanisms of the effects are not fully determined. In the present study, the cellula...
متن کاملInter-pulse Interval Affects the Size of Single-pulse TMS-induced Motor Evoked Potentials: a Reliability Study
Introduction: Measuring the size of motor evoked potentials (MEPs) induced by transcranial magnetic stimulation (TMS) is an investigational technique to show the level of corticospinal excitability however, some of the fundamental methodological aspects of TMS (such as the effects of inter-pulse intervals (IPI) on MEP size) are not fully understood, this issue raises concerns about the re...
متن کامل